Ten patients with tuberculosis of the wrist are reported. In three, the disease was limited to the tenosynovium and these patients were treated by synovectomy. Seven patients had disease involving the carpal bones. In six of these an arthrodesis of the wrist was done, and solid fusion was attained in four. In all of the patients the wrist disease became inactive under treatment with isoniazid and para-aminosalicyclic acid.