Tuberculosis in patients with various HLA phenotypes.

  title={Tuberculosis in patients with various HLA phenotypes.},
  author={Alexander Khomenko and Vitaly I. Litvinov and V P Chukanova and Lev E. Pospelov},
  volume={71 3},
Tuberculosis patients and healthy subjects from six ethnic groups of the Soviet Union were HLA-A, -B, -C, and DR typed. The frequencies of the HLA-A, -B and -C antigens differed amongst the ethnic groups. With all groups, however, patients with tuberculosis showed a significantly increased frequency of HLA-DR2 and a reduced frequency of HLA-DR3 type. Unfavourable dynamics of tuberculosis was significantly associated with an increased incidence of B15 and DR2 and a reduced incidence of B27 and… CONTINUE READING

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