Tuberculin-specific transfer factor in dogs.

  title={Tuberculin-specific transfer factor in dogs.},
  author={Michael R. Simon and Javier Silva and Doris Freier and Jan Bruner and R Wiliams},
  journal={Infection and immunity},
  volume={18 1},
Five mongrel dogs were sensitized to tuberculoprotein with Freund adjuvant, as determined by responses to tuberculin skin tests and by in vitro lymphocyte cultures. These animals served as blood donors for production of transfer factor. Nine mongrel dogs received single doses of transfer factor that was tuberculin specific. Successful transfer of tuberculin sensitivity as measured by lymphocyte transformations was achieved in five of nine animals. Canine lymphocyte cultures frequently showed… CONTINUE READING