Tubeimoside-1 inhibits the proliferation and activation of mouse T lymphocytes through signal transduction pathways.

@article{Huang2015Tubeimoside1IT,
  title={Tubeimoside-1 inhibits the proliferation and activation of mouse T lymphocytes through signal transduction pathways.},
  author={Yixuan Huang and Mengrou Ren and Ying Xiong and Tong V. Wang and Hongyu Chen and Xuming Deng and Jing Hua Lu},
  journal={Immunopharmacology and immunotoxicology},
  year={2015},
  volume={37 4},
  pages={366-74}
}
Tubeimoside-1 (TBMS1) is one of the important components in Bolbostemma paniculatum (Maxim.) Franque. In the study, its immunosuppressive effects on murine T lymphocyte responses were evaluated in vitro and in vivo. The data showed that TBMS1 inhibited ConA-induced T lymphocyte proliferation, decreased the ratio of CD4(+)/CD8(+), suppressed IL-2, IFN-γ, IL… CONTINUE READING