Tube fusion: making connections in branched tubular networks.

  title={Tube fusion: making connections in branched tubular networks.},
  author={Sara Caviglia and Stefan Luschnig},
  journal={Seminars in cell & developmental biology},
Organs like the vertebrate vascular system and the insect tracheal system develop from separate primordia that undergo fusion events to form interconnected tubular networks. Although the correct pattern of tubular connections (anastomoses) in these organs is crucial for their normal function, the cellular and molecular mechanisms that govern tube fusion are only beginning to be understood. The process of tube fusion involves tip cell specification, cell-cell recognition and contact formation… CONTINUE READING
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