Tryptophan catabolism via kynurenine production in Streptomyces coelicolor: identification of three genes coding for the enzymes of tryptophan to anthranilate pathway

Abstract

Most enzymes involved in tryptophan catabolism via kynurenine formation are highly conserved in Prokaryotes and Eukaryotes. In humans, alterations of this pathway have been related to different pathologies mainly involving the central nervous system. In Bacteria, tryptophan and some of its derivates are important antibiotic precursors. Tryptophan… (More)
DOI: 10.1007/s00253-011-3833-y

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@article{Zummo2011TryptophanCV, title={Tryptophan catabolism via kynurenine production in Streptomyces coelicolor: identification of three genes coding for the enzymes of tryptophan to anthranilate pathway}, author={Francesco Paolo Zummo and Sandra Marineo and Amy Pace and Federica Civiletti and Annarita Giardina and Anna Maria Puglia}, journal={Applied Microbiology and Biotechnology}, year={2011}, volume={94}, pages={719-728} }