Tryptophan- and arginine-rich antimicrobial peptides: structures and mechanisms of action.

@article{Chan2006TryptophanAA,
  title={Tryptophan- and arginine-rich antimicrobial peptides: structures and mechanisms of action.},
  author={David I. Chan and Elmar J Prenner and Hans J. Vogel},
  journal={Biochimica et biophysica acta},
  year={2006},
  volume={1758 9},
  pages={
          1184-202
        }
}
Antimicrobial peptides encompass a number of different classes, including those that are rich in a particular amino acid. An important subset are peptides rich in Arg and Trp residues, such as indolicidin and tritrpticin, that have broad and potent antimicrobial activity. The importance of these two amino acids for antimicrobial activity was highlighted through the screening of a complete combinatorial library of hexapeptides. These residues possess some crucial chemical properties that make… Expand
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