Tryptophan 140 is important, but serine 141 Is essential for the formation of the integrated conformation of staphylococcal nuclease.


A series of N-terminal fragments of staphylococcal nuclease with different chain lengths has been taken as an in vitro nascent peptide folding model. Previous studies have shown that nascent peptide folding of the nuclease may begin early in the synthetic process with the content of ordered secondary structure increases with increasing peptide chain length… (More)


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