Tryptoline-3-hydroxypyridinaldoxime conjugates as efficient reactivators of phosphylated human acetyl and butyrylcholinesterases.

@article{Renou2014Tryptoline3hydroxypyridinaldoximeCA,
  title={Tryptoline-3-hydroxypyridinaldoxime conjugates as efficient reactivators of phosphylated human acetyl and butyrylcholinesterases.},
  author={Julien Renou and M{\'e}lanie Loiodice and M{\'e}lanie Arbol{\'e}as and Rachid Baati and Ludovic Jean and Florian Nachon and Pierre-Yves Renard},
  journal={Chemical communications},
  year={2014},
  volume={50 30},
  pages={
          3947-50
        }
}
Two promising uncharged reactivators for inhibited human BChE and AChE have been described. These compounds show an ability to reactivate VX-inhibited BChE largely superior to those of known pyridinium aldoximes. Moreover, these oximes also exhibit a good ability to reactivate VX-, tabun- and paraoxon-inhibited human AChE. 

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