Tryptamine serves as a proligand of the AhR transcriptional pathway whose activation is dependent of monoamine oxidases.

@article{Bergander2012TryptamineSA,
  title={Tryptamine serves as a proligand of the AhR transcriptional pathway whose activation is dependent of monoamine oxidases.},
  author={Linda Vikstr{\"o}m Bergander and Wen Wen Cai and Bernward Klocke and Martin Seifert and Ingemar Pongratz},
  journal={Molecular endocrinology},
  year={2012},
  volume={26 9},
  pages={1542-51}
}
The function of the aryl hydrocarbon receptor (AhR) in mediating the biological effect to environmental pollutants is well established. However, accumulated evidence indicates a wide range of physiological and pathological functions mediated by the AhR, suggesting the existence of endogenous AhR ligand(s). The nature of an AhR ligand remain elusive; however… CONTINUE READING

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