Tryptamine-N-methyltransferase activity in brain tissue: a re-examination

@article{Boarder1976TryptamineNmethyltransferaseAI,
  title={Tryptamine-N-methyltransferase activity in brain tissue: a re-examination},
  author={Michael R. Boarder and Richard Rodnight},
  journal={Brain Research},
  year={1976},
  volume={114},
  pages={359-364}
}
It has been claimed that brain tissue from both animals and man contains an N-methyltransferase enzyme which can methylate tryptamine to form N-methyltryptamine (NMT) and N,N-dimethyltryptamine (DMT). Should the existence of such an enzyme in brain become soundly established it could prove a significant factor in the pathogenesis of some forms of psychotic illness in man 29. The parental administration of DMT to human subjects induces a model psychosis. Both S-adenosylmethionine (SAM) 1,3,12,14… Expand
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