Trypanosoma cruzi does not induce apoptosis in murine fibroblasts.

  title={Trypanosoma cruzi does not induce apoptosis in murine fibroblasts.},
  author={Raymond K. Clark and Raymond E. Kuhn},
  volume={118 ( Pt 2)},
The intracellular cycle of Trypanosoma cruzi in mammalian host cells involves the differentiation of dividing amastigote forms into flagellated trypomastigote forms. The mechanism(s) regulating the growth and differentiation of the intracellular parasites is (are) not known. The number of parasites in infected cells can be several hundred and may be enough to induce apoptosis, a suicide-like death programme, generating products (e.g. nuclear proteins) that could function as signals to initiate… CONTINUE READING

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