Trypanosoma cruzi TcSRPK, the first protozoan member of the SRPK family, is biochemically and functionally conserved with metazoan SR protein-specific kinases.

Abstract

A novel SR protein-specific kinase (SRPK) from the SRPK family was identified for the first time in a protozoan organism. The primary structure of the protein, named TcSRPK, presents a significant degree of identity with other metazoan members of the family. In vitro phosphorylation experiments showed that TcSRPK has the same substrate specificity relative… (More)

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@article{Portal2003TrypanosomaCT, title={Trypanosoma cruzi TcSRPK, the first protozoan member of the SRPK family, is biochemically and functionally conserved with metazoan SR protein-specific kinases.}, author={Daniel del Portal and Guillermo S Lobo and Sebasti{\'a}n Kadener and Jayendra Prasad and Joaqu{\'i}n M Espinosa and C. M. Pereira and Zhaohua Tang and R. X. Lin and James L Manley and Alberto R. Kornblihtt and Mirtha M. Flawi{\'a} and Hector Norberto Torres}, journal={Molecular and biochemical parasitology}, year={2003}, volume={127 1}, pages={9-21} }