Trypanosoma cruzi IIc: Phylogenetic and Phylogeographic Insights from Sequence and Microsatellite Analysis and Potential Impact on Emergent Chagas Disease

@inproceedings{Llewellyn2009TrypanosomaCI,
  title={Trypanosoma cruzi IIc: Phylogenetic and Phylogeographic Insights from Sequence and Microsatellite Analysis and Potential Impact on Emergent Chagas Disease},
  author={Martin Stephen Llewellyn and Michael David Lewis and N. Sebasti{\'a}n Acosta and Matthew Ming Chong Yeo and Hern{\'a}n Jos{\'e} Carrasco and Maikell J. Segovia and Jorge Vargas and Faustino Torrico Torrico and Michael Alexander Miles and Michael W. Gaunt},
  booktitle={PLoS neglected tropical diseases},
  year={2009}
}
Trypanosoma cruzi, the etiological agent of Chagas disease, is highly genetically diverse. Numerous lines of evidence point to the existence of six stable genetic lineages or DTUs: TcI, TcIIa, TcIIb, TcIIc, TcIId, and TcIIe. Molecular dating suggests that T. cruzi is likely to have been an endemic infection of neotropical mammalian fauna for many millions of years. Here we have applied a panel of 49 polymorphic microsatellite markers developed from the online T. cruzi genome to document genetic… CONTINUE READING

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