Trypanosoma cruzi: the major cysteinyl proteinase (cruzipain) is a relevant immunogen of parasite acidic antigens (FIII).

@article{Laderach1996TrypanosomaCT,
  title={Trypanosoma cruzi: the major cysteinyl proteinase (cruzipain) is a relevant immunogen of parasite acidic antigens (FIII).},
  author={Diego Jos{\'e} Laderach and Fabio M Cerban and Claudia Cristina Motr{\'a}n and E Vottero de Cima and Susana Gea},
  journal={International journal for parasitology},
  year={1996},
  volume={26 11},
  pages={
          1249-54
        }
}
This study examined the immune responses induced by cruzipain, a well-characterized T. cruzi antigen, to determine whether it is a relevant immunogen among the parasite acidic antigens (FIII), for which some biological properties have been studied previously. Humoral and cellular immune responses were investigated in BALB/C mice after immunization with cruzipain or FIII. Skin tests revealed immediate type-hypersensitivity (ITH) and delayed-type hypersensitivity (DTH) reactions to cruzipain in… CONTINUE READING

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