Trypanosoma cruzi: modification of macrophage function during infection

  title={Trypanosoma cruzi: modification of macrophage function during infection},
  author={N M Nogueira and Saimon Gordon and Zanvil Alexander Cohn},
  journal={The Journal of Experimental Medicine},
  pages={157 - 171}
Infection of mice with Trypanosoma cruzi and subsequent intraperitoneal challenge with heat-killed trypanosomes elicits peritoneal macrophages which display in vitro microbicidal activity against trypomastigotes of T. cruzi. These cells also display other activated properties including rapid spreading, intense membrane activity, secretion of high levels of… CONTINUE READING

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