Trypanosoma cruzi: antiprotozoal activity of parthenolide obtained from Tanacetum parthenium (L.) Schultz Bip. (Asteraceae, Compositae) against epimastigote and amastigote forms.

@article{Izumi2008TrypanosomaCA,
  title={Trypanosoma cruzi: antiprotozoal activity of parthenolide obtained from Tanacetum parthenium (L.) Schultz Bip. (Asteraceae, Compositae) against epimastigote and amastigote forms.},
  author={Erika Izumi and Luis G. Morello and T{\^a}nia Ueda-Nakamura and Sueli Fumie Yamada-Ogatta and Benedito Prado Dias del Filho and Di{\'o}genes Apar{\'i}cio Garcia Cortez and Izabel Cristina Piloto Ferreira and Jose Andr{\'e}s Morgado-D{\'i}az and Celso Vataru Nakamura},
  journal={Experimental parasitology},
  year={2008},
  volume={118 3},
  pages={
          324-30
        }
}
This study reports the activity of crude extracts, fractions and parthenolide (pure compound) obtained from Tanacetum parthenium against two forms of the parasite Trypanosoma cruzi. Feverfew is a traditional herbal medicine that has been used for the treatment of migraine, fever and arthritis. Activity against epimastigote forms was observed for crude extracts, fractions and parthenolide, and a progressive increase in the antitrypanosomal effect was observed in the course of the purification… CONTINUE READING
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