Trypanosoma brucei glycosomal ABC transporters: identification and membrane targeting.

  title={Trypanosoma brucei glycosomal ABC transporters: identification and membrane targeting.},
  author={C{\'e}dric Yernaux and Marc Fransen and Chantal Brees and Stephan Lorenzen and Paul A M Michels},
  journal={Molecular membrane biology},
  volume={23 2},
Trypanosomes contain unique peroxisome-like organelles designated glycosomes which sequester enzymes involved in a variety of metabolic processes including glycolysis. We identified three ABC transporters associated with the glycosomal membrane of Trypanosoma brucei. They were designated GAT1-3 for Glycosomal ABC Transporters. These polypeptides are so-called half-ABC transporters containing only one transmembrane domain and a single nucleotide-binding domain, like their homologues of mammalian… CONTINUE READING
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