Trypanosoma brucei Bloodstream Forms Depend upon Uptake of myo-Inositol for Golgi Complex Phosphatidylinositol Synthesis and Normal Cell Growth.

@article{GonzlezSalgado2015TrypanosomaBB,
  title={Trypanosoma brucei Bloodstream Forms Depend upon Uptake of myo-Inositol for Golgi Complex Phosphatidylinositol Synthesis and Normal Cell Growth.},
  author={Amaia Gonz{\'a}lez-Salgado and Michael E. Steinmann and Louise L. Major and Erwin Sigel and Jean-Louis Reymond and Terry K. Smith and Peter B{\"u}tikofer},
  journal={Eukaryotic cell},
  year={2015},
  volume={14 6},
  pages={616-24}
}
myo-Inositol is a building block for all inositol-containing phospholipids in eukaryotes. It can be synthesized de novo from glucose-6-phosphate in the cytosol and endoplasmic reticulum. Alternatively, it can be taken up from the environment via Na(+)- or H(+)-linked myo-inositol transporters. While Na(+)-coupled myo-inositol transporters are found… CONTINUE READING