Trypanocidal terpenoids from Laurus nobilis L.


Trypanocidal constituents of dried leaves of Laurus nobilis L. (Lauraceae) were examined. Activity-guided fractionation of the methanol extract resulted in the isolation of two guaianolides, dehydrocostus lactone (1) and zaluzanin D (2), and a new p-menthane hydroperoxide, (1R,4S)-1-hydroperoxy-p-menth-2-en-8-ol acetate (3). The minimum lethal… (More)


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@article{Uchiyama2002TrypanocidalTF, title={Trypanocidal terpenoids from Laurus nobilis L.}, author={Nahoko Uchiyama and Keiji Matsunaga and Fumiyuki Kiuchi and Gisho Honda and Akiko Tsubouchi and Junko Nakajima-Shimada and Takashi Aoki}, journal={Chemical & pharmaceutical bulletin}, year={2002}, volume={50 11}, pages={1514-6} }