Trypanocidal constituents in plants 3. Leaves of Garcinia intermedia and heartwood of Calophyllum brasiliense.

@article{Abe2004TrypanocidalCI,
  title={Trypanocidal constituents in plants 3. Leaves of Garcinia intermedia and heartwood of Calophyllum brasiliense.},
  author={Fumiko Abe and Shinya Nagafuji and Hikaru Okabe and Hiroshige Akahane and Elizabeth Estrada-Mu{\~n}iz and Maira Huerta-Reyes and R. Reyes-Chilpa},
  journal={Biological & pharmaceutical bulletin},
  year={2004},
  volume={27 1},
  pages={141-3}
}
The constituents of the leaves of Garcinia intermedia and heartwood of Calophyllum brasiliense were investigated based on their trypanocidal activity against epimastigotes of Trypanosoma cruzi, the etiologic agent of Chagas' disease. As the active components, the polyisoprenylated benzophenone derivative guttiferone A and the xanthone 8-desoxygartanin were isolated along with the biflavonoids podocarpusflavone A and amentoflavone, and friedelin from the former. Three xanthones, jacareubin, 6… CONTINUE READING

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