Trypan internetadvance publication at ajo.com Dec 11, 2002. Blue–assisted peeling of the internal limiting membrane during macular hole surgery

@article{Perrier2003TrypanIP,
  title={Trypan internetadvance publication at ajo.com Dec 11, 2002. Blue–assisted peeling of the internal limiting membrane during macular hole surgery},
  author={Manuel Perrier and Mikael Sebag},
  journal={American Journal of Ophthalmology},
  year={2003},
  volume={135},
  pages={903-905}
}
Abstract Purpose To evaluate the outcome of surgeries for macular holes using trypan blue to facilitate delamination of the internal limiting membrane. Design A retrospective series of 18 patients. Methods All patients underwent a three-port pars plana vitrectomy with internal limiting membrane delamination using trypan blue 0.06% to assist visualization. The main outcome measures were postoperative visual acuity and clinically evident retinal pigment epithelial changes. Results The median… Expand
Internal limiting membrane peeling with indocyanine green or trypan blue in macular hole surgery: a randomized trial.
TLDR
Although no statistically significant difference was detected for the primary end point, the better visual recovery in the TB group and the higher rate of persistent central scotomata in the ICG group justify a larger clinical trial. Expand
MACULAR HOLE CLOSURE WITH TRIAMCINOLONE-ASSISTED INTERNAL LIMITING MEMBRANE PEELING
TLDR
Triamcinolone-assisted internal limiting membrane peel is an effective surgical technique in macular hole surgery and Anatomic closure rates and visual outcomes compared favorably with published literature on macular holes surgery. Expand
IN VIVO SAFETY OF TRYPAN BLUE USE IN VITREORETINAL SURGERY
TLDR
Evaluating “in vivo” safety of trypan blue in patients undergoing TB-assisted internal limiting membrane or epiretinal membrane peeling found no deleterious effects of TB were observed in this study. Expand
A comparison of outcomes after indocyanine green and trypan blue assisted internal limiting membrane peeling during macular hole surgery
TLDR
TB appears to be less toxic than ICG when used in dye assisted peeling of ILM during macular hole repair as reflected by the better visual results in the TB group of patients. Expand
Functional outcome after trypan blue-assisted vitrectomy for macular pucker: a prospective, randomized, comparative trial.
TLDR
Trypan blue-assisted vitrectomy for macular pucker leads to good functional results with no dye-related adverse effects after short follow-up, and trypan blue might be especially applicable in cases in which the borders of the ERM are difficult to define. Expand
INDOCYANINE GREEN–ASSISTED INTERNAL LIMITING MEMBRANE PEELING FOR MACULAR HOLES: Toxicity?
TLDR
Indocyanine green usage during macular hole surgery was not associated with worse visual outcomes, suggesting possible toxic effects reported are not clinically significant, and ICG should be considered a safe option. Expand
Use of heavy Trypan blue in macular hole surgery
TLDR
Heavy Trypan blue can be delivered efficiently to the retinal surface without the need for an AFX and appears to have little retinal toxicity. Expand
[Evaluation of trypan-blue toxicity in macular hole surgery with electroretinography].
TLDR
No significant retinal toxicity of TB staining could be clinically detected in macular hole surgery with TB-assisted internal limiting membrane peeling through the performance of electroretinograms (ERGs). Expand
QUANTIFICATION OF CONTRAST RECOGNIZABILITY IN SEQUENTIAL EPIRETINAL MEMBRANE REMOVAL AND INTERNAL LIMITING MEMBRANE PEELING IN TRYPAN BLUE–ASSISTED MACULAR SURGERY
TLDR
Trypan blue's staining capacity of the internal limiting membrane is similar to that of brilliant blue G but significantly inferior compared with indocyanine green, and represents a useful vital dye for chromovitrectomy, particularly in the presence of ERM, where it allows a sequential approach. Expand
ULTRASTRUCTURE AND RETINAL IMAGING OF INTERNAL LIMITING MEMBRANE: A Clinicopathologic Correlation of Trypan Blue Stain in Macular Hole Surgery
TLDR
Trypan blue stain from these data seems to improve the ease and completeness of the ILM peeling (assessed clinically) and does not show any signs of toxicity. Expand
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PER OPERATIVE TRYPAN BLUE VITAL STAINING OF CORNEAL ENDOTHELIUM
  • M. Norn
  • Medicine
  • Acta ophthalmologica
  • 1980
An 0.1% aqueous trypan blue solution was injected into the anterior chamber during cataract extraction for the purpose of disclosing endothelial cell damage if present.