Trunk sensorimotor cortex is essential for autonomous weight-supported locomotion in adult rats spinalized as P1/P2 neonates.

@article{Giszter2008TrunkSC,
  title={Trunk sensorimotor cortex is essential for autonomous weight-supported locomotion in adult rats spinalized as P1/P2 neonates.},
  author={Simon F. Giszter and Michelle R. Davies and Arun Ramakrishnan and Ubong Ime Udoekwere and William J. Kargo},
  journal={Journal of neurophysiology},
  year={2008},
  volume={100 2},
  pages={839-51}
}
Unlike adult spinalized rats, approximately 20% of rats spinalized as postnatal day 1 or 2 (P1/P2) neonates achieve autonomous hindlimb weight support. Cortical representations of mid/low trunk occur only in such rats with high weight support. However, the importance of hindlimb/trunk motor cortex in function of spinalized rats remains unclear. We tested the importance of trunk sensorimotor cortex in their locomotion using lesions guided by cortical microstimulation in P1/P2 weight-supporting… CONTINUE READING
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