Truncated estrogen receptor product-1 stimulates estrogen receptor alpha transcriptional activity by titration of repressor proteins.

@article{Lin2003TruncatedER,
  title={Truncated estrogen receptor product-1 stimulates estrogen receptor alpha transcriptional activity by titration of repressor proteins.},
  author={Vicky Yu-tzu Lin and Eileen M. Resnick and Margaret A. Shupnik},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 40},
  pages={
          38125-31
        }
}
The truncated estrogen receptor product-1 (TERP-1, or TERP) is a pituitary-specific isoform of estrogen receptor alpha (ERalpha), and its expression is regulated by estrogen. TERP modulates the transcriptional activity of ERalpha but has no independent effect on transcription of estrogen-response element-containing promoters. At low concentrations, TERP stimulates ERalpha transcriptional activity in transient transfection assays. At TERP concentrations equal to or greater than full-length… CONTINUE READING
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