Truncated HLA-G isoforms are retained in the endoplasmic reticulum and insufficiently provide HLA-E ligands.

@article{Ulbrecht2004TruncatedHI,
  title={Truncated HLA-G isoforms are retained in the endoplasmic reticulum and insufficiently provide HLA-E ligands.},
  author={Matthias Ulbrecht and Sabine Maier and Valeska Hofmeister and Christine S. Falk and Andrew G. Brooks and Michael T Mcmaster and Elisabeth H. Weiss},
  journal={Human immunology},
  year={2004},
  volume={65 3},
  pages={200-8}
}
The preferential expression of the non-polymorphic human leukocyte antigen G (HLA-G) on invading extravillous cytotrophoblast cells that are, with the exception of HLA-C and -E, HLA class I negative led to the hypothesis that HLA-G plays a major role in controlling the effector functions of the large granular leukocytes (LGL), a specialized natural killer (NK) cell population present in large numbers in the decidua. Transcription of the HLA-G gene is characterized by extensive alternative… CONTINUE READING
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