True vocal fold nodules: the role of differential diagnosis

  title={True vocal fold nodules: the role of differential diagnosis},
  author={Melda Kunduk and Andrew J. McWhorter},
  journal={Current Opinion in Otolaryngology \& Head and Neck Surgery},
Purpose of reviewThe present article aims to discuss the current reviews and the literature published regarding the differential diagnosis of vocal fold nodules with emphasis on diagnosis and nomenclature. Recent findingsBenign lesions of the vocal folds, including nodules, continue to challenge practitioners in nomenclature uniformity and even histologic diagnosis. Utilization of molecular techniques is helping to better understand Reinke's space and to better differentiate these lesions. This… 

Vocal nodules management

  • M. BirchallP. Carding
  • Medicine
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
  • 2019
The authors suggest the development of evidence‐based guidelines for UK practice, including poorly defined nomenclature, the natural history of paediatric vocal nodules, the establishment of criteria to measure successful treatment, optimal configuration of speech therapy regimens and the rationale for surgical intervention.

[Benign vocal fold lesions].

Benign vocal fold lesions are grouped in lesions arising from the epithelium like papillomas, lesions affecting the Reinke's space (nodules, polyps, cysts, Reinkes's edema as a form of chronic

Surgical and Non-Surgical Treatment Outcome Assessed by Voice Handicap Index of Patients with Vocal Fold Nodule

VHI (Voice Handicap Index) was applied as outcome measures for assessing the efficiency of intervention between surgical and non-surgical groups for vocal nodules refractory to voice therapy.

Effectiveness of voice therapy in patients with vocal fold nodules: a systematic search and narrative review

Improved evidence is required to suggest that short period treatments are as beneficial as traditional therapy programs, and using telepractice voice therapy may be an achievable and practical way of delivering treatment and enhance adherence to therapy.

Hoarseness-causes and treatments.

Voice therapy, vocal cord surgery, and drug therapy for appropriate groups of patients with hoarseness are well documented as effective by the available evidence.

High speed digital videolaringoscopy: evaluation of vocal nodules and cysts in women.

The analysis of Digital kymography suggests that the presence of the vocal fold nodules and the vocal cysts tend to restrict more to the maximum and minimum opening of theocal fold and the dominant amplitude of the opening variation in the middle region of the glottis.

Patient-Reported Factors Associated with the Onset of Hyperfunctional Voice Disorders

The results support the general clinical view that PVH is most strongly related to the gradual accumulated effects of phonotrauma, while NPVH has a more heterogeneous etiology.

Changes in a Daily Phonotrauma Index After Laryngeal Surgery and Voice Therapy: Implications for the Role of Daily Voice Use in the Etiology and Pathophysiology of Phonotraumatic Vocal Hyperfunction.

The DPI produced the expected pattern of improved ambulatory voice use across laryngeal surgery and postsurgical voice therapy in a group of patients with PVH, providing new objective information about the role of daily voice use in the etiology and pathophysiology of PVH.

An Updated Theoretical Framework for Vocal Hyperfunction.

An updated and expanded framework for VH is proposed to help guide future research, particularly the design of longitudinal studies, which can lead to a refinement in knowledge about the etiology and pathophysiology of VH-related disorders.



Update on the etiology, diagnosis, and treatment of vocal fold nodules, polyps, and cysts

  • M. Johns
  • Medicine
    Current opinion in otolaryngology & head and neck surgery
  • 2003
Clinical and basic research has furthered the understanding of benign vocal fold lesions and has expanded the diagnostic and therapeutic armamentarium for patients with dysphonia arising from these lesions.

Management of Benign Vocal Fold Lesions: A Survey of Current Opinion and Practice

Traditional diagnostic categories do not seem to be useful guides to treatment, and may need to be reevaluated in light of improvements in diagnostic technology and surgical technique.

Exudative laryngeal diseases of Reinke's space: a clinicohistopathological framing.

To establish the relationship between the macroscopic and histologic diagnosis of nodules, polyps, and Reinke's edema of the true vocal folds and to propose a clearer clinical definition of them, a suggestion is to consider polyps as "older" lesions and nodules as "younger" lesions.

Lamina Propria of the Mucosa of Benign Lesions of the Vocal Folds

Investigations demonstrate characteristic histopathologic features for three clinically well‐defined lesions: 1) vocal fold polyps, 2) Reinke edema, and 3) vocal Fold nodules.

Utility of Voice Therapy in the Management of Vocal Fold Polyps and Cysts

  • Seth M. CohenC. Garrett
  • Medicine
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2007

The Evolution of Diagnosing Benign Vocal Fold Lesions: From Vague to Specific

Abstract The evaluation and treatment process for dysphonia due to benign vocal fold lesions (BVFL) can often be a complex and confusing process for clinicians as well as patients. There is no one ...

Benign Pathologic Responses of the Larynx

A better understanding of the effects of excessive deposition of structural glycoproteins such as fibronectin and of abnormal proteoglycan deposition may lead to a better characterization of vocal fold disease and its causation and, ultimately, better treatment.

Benign pathologic responses of the larynx.

A better understanding of the effects of excessive deposition of structural glycoproteins such as fibronectin and of abnormal proteoglycan deposition may lead to a better characterization of vocal fold disease and its causation and, ultimately, better treatment.

Nomenclature of voice disorders and vocal pathology.

Quality-of-Life Impact of Non-Neoplastic Voice Disorders: A Meta-Analysis

Both patients with neurologic disease and patients with inflammatory or traumatic laryngeal disorders had changes in SF-36 subdomains similar to those of patients with other chronic disease states, and neurologic voice disorders have the greatest impact.