TruMatch - a BLAST post-processor that identifies bona fide sequence matches to genome assemblies

@article{Li2005TruMatchA,
  title={TruMatch - a BLAST post-processor that identifies bona fide sequence matches to genome assemblies},
  author={Weixi Li and Cathryn J. Rehmeyer and Chuck Staben and Mark L. Farman},
  journal={Bioinformatics},
  year={2005},
  volume={21 9},
  pages={2097-8}
}
SUMMARY BLAST is a widely used alignment tool for detecting matches between a query sequence and entries in nucleotide sequence databases. Matches (high-scoring pairs, HSPs) are assigned a score based on alignment length and quality and, by default, are reported with the top-scoring matches listed first. For certain types of searches, however, this method of reporting is not optimal. This is particularly true when searching a genome sequence with a query that was derived from the same genome… CONTINUE READING
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