Trospium chloride improves overactive bladder symptoms: a multicenter phase III trial.

  title={Trospium chloride improves overactive bladder symptoms: a multicenter phase III trial.},
  author={Norman R. Zinner and Marc M Gittelman and Richard P. Harris and Jacques Susset and Angelo Kanelos and Stephen M Auerbach},
  journal={The Journal of urology},
  volume={171 6 Pt 1},
  pages={2311-5, quiz 2435}
PURPOSE Trospium chloride is an anticholinergic agent with predominantly peripheral nonselective antimuscarinic activity lacking central nervous system effects. It has no known drug-drug interactions, an advantage for patients taking many medications. Because these qualities may provide added benefit when treating patients with symptoms associated with overactive bladder (OAB) and urge incontinence, we studied the effectiveness of trospium in treating these conditions. MATERIALS AND METHODS… CONTINUE READING
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Psychometric validation of an urgency severity scale (IUSS) for patients with overactive bladder

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Efficacy and tolerability of trospium chloride and tolterodine in 234 patients with urgeTABLE

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