Troponin T autoantibodies correlate with chronic cardiomyopathy in human Chagas disease.

@article{Nunes2013TroponinTA,
  title={Troponin T autoantibodies correlate with chronic cardiomyopathy in human Chagas disease.},
  author={Daniela Ferreira Nunes and Paulo Marcos Matta Guedes and Cl{\'e}ber de Mesquita Andrade and Ant{\^o}nia Cl{\'a}udia J{\'a}come da C{\^a}mara and Egler Chiari and L{\'u}cia Maria da Cunha Galv{\~a}o},
  journal={Tropical medicine & international health : TM & IH},
  year={2013},
  volume={18 10},
  pages={1180-92}
}
OBJECTIVE To evaluate the potential involvement of anti-Trypanosoma cruzi and cardiac protein antibody (IgG total and isotypes) production and their possible association with different clinical forms of human chronic Chagas disease. METHODS IgG total and isotypes were measured by ELISA, using epimastigote and trypomastigote forms of T. cruzi as antigens and human cardiac proteins (myosin and troponin T) in sera of patients with indeterminate (IND, n = 72), cardiac (CARD, n = 47) and digestive… CONTINUE READING
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