Tropomyosin and troponin regulation of wild type and E93K mutant actin filaments from Drosophila flight muscle. Charge reversal on actin changes actin-tropomyosin from on to off state.

Abstract

In the Drosophila flight muscle actin mutant E93K there is a charge reversal on the surface of actin close to the proposed position of tropomyosin when it is in the off state. Using a quantitative in vitro motility assay we have found that the wild type Drosophila ACT88F actin behaved like rabbit skeletal muscle actin when tropomyosin and troponin were… (More)

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Cite this paper

@article{Bing1998TropomyosinAT, title={Tropomyosin and troponin regulation of wild type and E93K mutant actin filaments from Drosophila flight muscle. Charge reversal on actin changes actin-tropomyosin from on to off state.}, author={Wenzeng Bing and Azam Razzaq and John C. Sparrow and Steven B. Marston}, journal={The Journal of biological chemistry}, year={1998}, volume={273 24}, pages={15016-21} }