Tropisetron reduces postoperative vomiting in children undergoing tonsillectomy.

@article{Jensen2000TropisetronRP,
  title={Tropisetron reduces postoperative vomiting in children undergoing tonsillectomy.},
  author={Ane B Jensen and Dr. B{\"a}rbel Christiansen and Kingsley Coulthard and Abigail Wilkins and Gregory F. Roberts and Jan Harm van der Walt and Magnhild Rasmussen},
  journal={Paediatric anaesthesia},
  year={2000},
  volume={10 1},
  pages={69-75}
}
In this patient, parent and investigator blinded, randomized, placebo-controlled study, children undergoing tonsillectomy (mean age 6.4 years) received either intravenous placebo (n=36) or tropisetron 0.2 mg.kg-1 up to 5 mg (n=35) at induction of anaesthesia with halothane, nitrous oxide and oxygen. Morphine and paracetamol were given in theatre for postoperative pain. Episodes of vomiting were recorded during the first 24 h after surgery. Intravenous tropisetron was significantly (P<0.001, chi… CONTINUE READING