Trophoblastic remodeling in normal and preeclamptic pregnancies: implication of cytokines.

  title={Trophoblastic remodeling in normal and preeclamptic pregnancies: implication of cytokines.},
  author={Abdelaziz Kharfi and Yves Gigu{\`e}re and Vincent Sapin and Jacques Masse and Bernard Dastugue and J M Forest},
  journal={Clinical biochemistry},
  volume={36 5},
OBJECTIVE To summarize the recent knowledge on the implications of placenta and cytokines in normal and preeclamptic pregnancies. DATA SOURCES A literature search was conducted of applicable articles related to interactions between trophoblast and cytokines in generating preeclampsia. CONCLUSIONS The initiating event in preeclampsia has been postulated to be the reduced uteroplacental perfusion as a result of abnormal extravillous cytotrophoblast invasion and remodeling of the uterine… CONTINUE READING


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