Trophoblast migration during human placental implantation.

  title={Trophoblast migration during human placental implantation.},
  author={T D Burrows and Adam Philip King and Yung Way Loke},
  journal={Human reproduction update},
  volume={2 4},
During the process of implantation in humans, fetal trophoblast cells invade and migrate into the maternal decidua. During this migration, trophoblast cells destroy the wall of the maternal spiral arteries, converting them from muscular vessels into flaccid sinusoidal sacs. This vascular transformation is important to ensure an adequate blood supply to the feto-placental unit. Both cell-cell and cell-matrix interactions are important for trophoblast invasion of the decidual stroma and decidual… CONTINUE READING

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