Trophic regulation of synaptic plasticity.

Abstract

Trophins are now known to acutely regulate synaptic plasticity, in addition to exerting long-recognized actions on neuronal survival and development. To begin elucidating underlying mechanisms, cultured dissociated hippocampal neurons were examined by whole-cell patch-clamp recording. BDNF (brain derived neurotrophic factor) specifically and selectively… (More)

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