Trophic regulation of acetylcholinesterase isoenzymes in adult mammalian skeletal muscles

@article{Fernandez1992TrophicRO,
  title={Trophic regulation of acetylcholinesterase isoenzymes in adult mammalian skeletal muscles},
  author={Hugo L. Fernandez and Cheryl A. Hodges-Savola},
  journal={Neurochemical Research},
  year={1992},
  volume={17},
  pages={115-124}
}
This work addresses the physiological regulation of skeletal muscle acetylcholinesterase (AChE) isoforms by examining endplate-enriched samples from adult rat gracilis muscles 48 h after: lowintensity treadmill exercise; obturator nerve transection; nerve impulse conduction blockade by tetrodotoxin; acetylcholine (ACh) receptor (AChR) inactivation by α-bungarotoxin; and, addition of obturator nerve extracts to muscles in organ culture. Results document the important role(s) of functional AChRs… CONTINUE READING