Trophic and tropic effects of striatal astrocytes on cografted mesencephalic dopamine neurons and their axons.

@article{Pierret1998TrophicAT,
  title={Trophic and tropic effects of striatal astrocytes on cografted mesencephalic dopamine neurons and their axons.},
  author={Philippe Pierret and Nancy Quenneville and Sabine Vandaele and R Abbaszadeh and Christian Lanct{\^o}t and Philippe Crine and Guy Doucet},
  journal={Journal of neuroscience research},
  year={1998},
  volume={51 1},
  pages={23-40}
}
Astrocytes from the ventral mesencephalon and from the striatum respectively promote the dendritic and axonal arborization of dopamine (DA) neurons in vitro. To test this response in vivo, astrocytes in primary cultures from the neonatal cerebral cortex, ventral mesencephalon, or striatum were coimplanted with fetal ventral mesencephalic tissue into the intact or DA-denervated striatum of adult rats and these cografts examined after 3-6 months by tyrosine hydroxylase (TH) immunohistochemistry… CONTINUE READING

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