Trogocytosis is a gateway to characterize functional diversity in melanoma-specific CD8+ T cell clones.

Abstract

Trogocytosis, the transfer of membrane patches from target to immune effector cells, is a signature of tumor-T cell interaction. In this study, we used the trogocytosis phenomenon to study functional diversity within tumor-specific T cell clones with identical TCR specificity. MART-1(26-35)-specific CD8 T cell clones, which differed in their trogocytosis… (More)
DOI: 10.4049/jimmunol.1101429

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@article{Uzana2012TrogocytosisIA, title={Trogocytosis is a gateway to characterize functional diversity in melanoma-specific CD8+ T cell clones.}, author={Ronny Uzana and Galit Eisenberg and Yael Sagi and Shoshana Frankenburg and Sharon Merims and Ninette Amariglio and Eitan Yefenof and Tamar Peretz and Arthur Machlenkin and Michal M. Lotem}, journal={Journal of immunology}, year={2012}, volume={188 2}, pages={632-40} }