Troglitazone inhibits isolated cell proliferation, and induces apoptosis in isolated rat mesangial cells.

@article{Tsuchiya2003TroglitazoneII,
  title={Troglitazone inhibits isolated cell proliferation, and induces apoptosis in isolated rat mesangial cells.},
  author={Takahumi Tsuchiya and H. Shimizu and Kenju Shimomura and Masatomo Mori},
  journal={American journal of nephrology},
  year={2003},
  volume={23 4},
  pages={222-8}
}
BACKGROUND/AIMS Troglitazone is one of thiazolidinedione derivatives as a high affinity ligand for peroxisome proliferator-activated receptor-gamma (PPAR-gamma). The in vivo studies demonstrated that troglitazone ameliorated microalbuminuria. There have been few reports about direct effect of thiazolidinedione derivatives on mesangial cell function. We… CONTINUE READING