Troglitazone induced apoptosis via PPARγ activated POX-induced ROS formation in HT29 cells.

Abstract

OBJECTIVE In order to investigate the potential mechanisms in troglitazone-induced apoptosis in HT29 cells, the effects of PPARγ and POX-induced ROS were explored. METHODS [3- (4, 5)-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide (MTT) assay, Annexin V and PI staining using FACS, plasmid transfection, ROS formation detected by DCFH staining, RNA… (More)
DOI: 10.3967/0895-3988.2011.04.010

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