Trofosides A and B and other cytostatic steroid-derived compounds from the far east starfish Trofodiscus über

  title={Trofosides A and B and other cytostatic steroid-derived compounds from the far east starfish Trofodiscus {\"u}ber},
  author={Eleonora V Levina and Anatoly I. Kalinovsky and P. V. Andriyashchenko and Natalia I. Menzorova and Pavel S. Dmitrenok},
  journal={Russian Journal of Bioorganic Chemistry},
Three new polar steroids identified as trofoside A, 20R,24S)-24-O-(3-O-methyl-β-D-xylopyranosyl)-3β,6α,8,15β,24-pentahydroxy-5α-cholestane, its 22(23)-dehydro derivative (trofoside B), and 15-sulfooxy-(20R,24S)-5α-cholestane-3β,6β,8,15α,24-pentaol sodium salt, were isolated fromTrofodiscus über starfish extracts collected in the Sea of Ohotsk. Two known compounds, trofoside A aglycone, (20R,24S)-3β,6α,8,15β,24-pentahydroxy-5α-cholestane, and triseramide, (20R,24R,25S,22E)-24-methyl-3β6α,8,15… 
The Influence on LPS-Induced ROS Formation in Macrophages of Capelloside A, a New Steroid Glycoside from the Starfish Ogmaster capella
A new steroid glycoside was isolated from the ethanolic extract of the starfish Ogmaster capella along with the previously known coscinasteroside B, which decreased intracellular ROS levels in murine macrophages of the RAW 264.7 cell line at induction by endotoxic lipopolysaccharide from E. coli.
Marine Invertebrate Extracts Induce Colon Cancer Cell Death via ROS-Mediated DNA Oxidative Damage and Mitochondrial Impairment
It is postulate that reactive oxygen species (ROS) accumulation is responsible for the subsequent DNA damage, mitochondrial depolarization, and cell cycle arrest, ultimately inducing cell death by either apoptosis or necrosis.
Formation of the steroidal C-25 chiral center via the asymmetric alkylation methodology.
A novel approach for the preparation of steroids containing a chiral center at C-25 is reported, and the developed methodology was successfully applied to the synthesis of (25R)- and (25S)-cholestenoic acids as well as ( 25R- and ( 25S)-26-hydroxy brassinolides.
Chemical Constituents and Bioactivities of Starfish
The aim of this review is to provide an up‐to‐date review on the chemistry and bioactivity of compounds isolated from all kinds of starfish to illustrate the chemodiversity and biological significance of these constituents, along with their geographical distribution where it is discernible.
Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2007-2008.
  • D. Harvey
  • Chemistry, Medicine
    Mass spectrometry reviews
  • 2012
This review is the fifth update of the original review, published in 1999, on the application of MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of
New Polar Steroids from Starfish
A short review concerning new polar steroids isolated from starfish with 75 citations is given. This review covers the literature published from 2001 through 2007. The emphasis is on new structures,
Steroid glycosides from marine organisms
Structures, taxonomic distribution and biological activities of steroid glycosides isolated from marine organisms over the last 8-10 years are reviewed. The bibliography includes 130 references.


Phrygiasterol, a cytotoxic cyclopropane-containing polyhydroxysteroid, and related compounds from the pacific starfish Hippasteria phrygiana.
The new cyclopropane-containing steroid phrygiasterol (1) and steroid glycoside phrygioside B (2), along with previously known borealoside C (2a) and
Starfish saponins, 48. Isolation of fifteen sterol constituents (six glycosides and nine polyhydroxysteroids) from the starfish Solaster borealis.
Among the polyhydroxysteroid constituents, four (7-10) are new, and five (11-15) have previously been isolated from starfishes.
Chemical and biological investigation of the polar constituents of the starfish Luidia clathrata, collected in the Gulf of Mexico.
Ten new and three known polyhydroxysteroids were isolated from the starfish Luidia clathrata, collected from the offshore waters of the northern Gulf of Mexico, and they are all potent inhibitors of settlement.
Starfish saponins, part 49. New cytotoxic steroidal glycosides from the starfish Fromia monilis.
Nine new cytotoxic steroidal glycosides 1-9 have been isolated from the starfish Fromia monilis collected off New Caledonia, including the first tri-glycosides to be found among the group of glycoside of polyhydroxilated steroids from starfishes.
Minutosides A and B, antifungal sulfated steroid xylosides from the patagonian starfish Anasterias minuta.
Two new sulfated polyhydroxylated steroidal xylosides, minutosides A (1) and B (2), together with the known pycnopodioside B (3), have been isolated from the brine shrimp active fraction of the
Marine polar steroids
Structures, taxonomic distribution and biological activities of polar steroids isolated from various marine organisms over the last 8—10 years are considered. The peculiarities of steroid biogenesis
The composition of fetal fluids of the marsupial Macropus eugenii.
  • M. Renfree
  • Biology, Medicine
    Developmental biology
  • 1973
It is suggested that the second phase of growth of the embryo can be divided into two phases, one of increasing fetal autonomy, made possible by the differentiation of organ systems (some of which appear to be functional early), as well as by possible conversion of material in the yolk sac itself.
Determination of spermatozoan motility.
The motility of sea urchin spermatozoa upon dilution into seawater has been quantitatively determined and found to consist of three distinct periods: a short period of high motility without decrease in activity, a period of rapid decline in activity (which appears to be exponential), and a variable period of low activity.
Geny i razvitie organizma (Genes and Development of Organism)
  • Moscow: Nauka,
  • 1984