TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses.

Abstract

Neurotrophin signaling has been implicated in the processes of synapse formation and plasticity. To gain additional insight into the mechanism of BDNF and TrkB influence on synapse formation and synaptic plasticity, we generated a conditional knock-out for TrkB using the cre/loxp system. Using three different cre-expressing transgenic mice, three unique… (More)

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@article{Luikart2005TrkBHA, title={TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses.}, author={Bryan W Luikart and Serge Nef and Tuhin Virmani and Mark E. Lush and Yajuan J Liu and Ege T Kavalali and Luis F. Parada}, journal={The Journal of neuroscience : the official journal of the Society for Neuroscience}, year={2005}, volume={25 15}, pages={3774-86} }