TrkB and protein kinase Mζ regulate synaptic localization of PSD-95 in developing cortex.

Abstract

Postsynaptic density 95 (PSD-95), the major scaffold at excitatory synapses, is critical for synapse maturation and learning. In rodents, eye opening, the onset of pattern vision, triggers a rapid movement of PSD-95 from visual neuron somata to synapses. We showed previously that the PI3 kinase-Akt pathway downstream of BDNF/TrkB signaling stimulates… (More)
DOI: 10.1523/JNEUROSCI.2190-11.2011

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