Trk receptors: roles in neuronal signal transduction.

  title={Trk receptors: roles in neuronal signal transduction.},
  author={Eric J. Huang and Louis F Reichardt},
  journal={Annual review of biochemistry},
Trk receptors are a family of three receptor tyrosine kinases, each of which can be activated by one or more of four neurotrophins-nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophins 3 and 4 (NT3 and NT4). Neurotrophin signaling through these receptors regulates cell survival, proliferation, the fate of neural precursors, axon and dendrite growth and patterning, and the expression and activity of functionally important proteins, such as ion channels and… 

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