[Triterpenoids from roots of Rosa laevigata].


To study the triterpenoids from the roots of Rosa laevigata. The silica gel column chromatography was used to separate the chemical constituents from the roots of Rosa laevigata Michx. HPLC was used to analyze its purity, chemical and spectroscopy methods were used to determine their structures. 12 constituents were isolated and identified as(2R, 19R)methyl 2-acetyloxy-19- hydroxyl-3-oxo-urs-12-en-28-carboxylate(1), pomonic acid (2), 18, 19-seco, 2α, 3α-dihydroxy-19-oxo-urs-11, 13(18)-dien-28-oic acid(3), swinhoeic acid (4), myrianthic acid(5), 2α, 3β, 19α-trihydroxy-24-oxo-urs-12-en-oic acid (6), tormentic acid(7), arjunic acid (8), 1β-hydroxyeuscaphic acid(9), quadranoside Ⅷ (10), alpinoside(11), rubuside B (12). Compounds 1-4, 6, 9, 11-12 were obtained from this plant for the first time. Compounds 2-4, 6, 11-12 were obtained from the genus Rosa for the first time.

DOI: 10.4268/cjcmm20161216

Cite this paper

@article{Dai2016TriterpenoidsFR, title={[Triterpenoids from roots of Rosa laevigata].}, author={Hua-Nian Dai and Guo-xu Ma and Jie-ming Zhou and Xiao-Qing Zhong and Yan-Lin Zhou and Gao-Rong Lv and Yun-Qing Wang and Jing-quan Yuan and Xu-Dong Xu}, journal={Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica}, year={2016}, volume={41 12}, pages={2267-2272} }