• Biology, Medicine
  • Published in Phytotherapy research : PTR 2008
  • DOI:10.1002/ptr.2484

Triterpenoids and a sterol from the stem-bark of Styrax japonica and their protein tyrosine phosphatase 1B inhibitory activities.

@article{Kwon2008TriterpenoidsAA,
  title={Triterpenoids and a sterol from the stem-bark of Styrax japonica and their protein tyrosine phosphatase 1B inhibitory activities.},
  author={Joo-Hee Kwon and Min-jung Chang and Hyo-Won Seo and Jeong-Hun Lee and Byung-sun Min and MinKyun Na and Jin Cheol Kim and Mi Hee Woo and Jae Sue Choi and Hyeong Lee and Kihwan Bae},
  journal={Phytotherapy research : PTR},
  year={2008},
  volume={22 10},
  pages={
          1303-6
        }
}
Five pentacyclic triterpenoids (1-5) and a sterol (6) were isolated from the stem-bark of Styrax japonica. The six compounds, 1-6, were determined to be 3beta-acetoxy-28-hydroxyolean-12-ene (1), 3beta-acetoxyolean-12-en-28-acid (2), 3beta-acetoxyolean-12-en-28-aldehyde (3), 3beta-acetoxy-17beta-hydroxy-28-norolean-12-ene (4), taraxerol (5) and stigmasterol (6), respectively, by spectroscopic means, including the 2D-NMR technique. Compound 4 is a newly discovered natural compound. The protein… CONTINUE READING

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