• Corpus ID: 21981787

Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds.

@article{Maquart1999TriterpenesFC,
  title={Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds.},
  author={François Xavier Maquart and François Chastang and Amandine Sim{\'e}on and Philippe Birembaut and Philippe Gillery and Yanusz Wegrowski},
  journal={European journal of dermatology : EJD},
  year={1999},
  volume={9 4},
  pages={
          289-96
        }
}
Titrated Extract from Centella asiatica (TECA) is a drug which has been used for many years in Europe for the treatment of wound healing defects. It is a reconstituted mixture of 3 triterpenes extracted from the plant, asiatic acid, madecassic acid and asiaticoside. In this report, we studied the effects of TECA and its separated components in the wound chamber model described by Schilling et al. Stainless steel wound chambers were surgically inserted under the skin of rats and received serial… 
AQUEOUS EXTRACT OF CENTELLA ASIATICA AS A POTENTIAL ANTI-KELOID AGENT
Centella asiatica (CA) is a reputed medicinal plant that has been shown to have pharmacological effect on skin wound healing. The aim of the study was done to assess the effects of aqueous extract of
HE SCIENCE SUPPORTING TITRATED EXTRACT OF CENTELLA ASIATICA
  • 2004
Titrated Extract of Centella Asiatica (TECA) is a reconstituted mixture of three triterpenes extracted from the plant and is being used in Europe in wound healing drugs. TECA has been shown to
The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats.
TLDR
The results suggest the potential use of Centella asiatica and its active ingredient as anti-gastric ulcers drugs.
Matrix metalloproteinase, hyaluronidase and elastase inhibitory potential of standardized extract of Centella asiatica
Abstract Context: Centella asiatica (L.) Urban (Apiaceae), a valuable herb described in Ayurveda, is used in the indigenous system of medicine as a tonic to treat skin diseases. Objective: Centella
In vitro keratinocyte antiproliferant effect of Centella asiatica extract and triterpenoid saponins.
TLDR
Results suggest that the potential use of C. asiatica extracts as a topical anti-psoriatic agent is worthy of further investigation.
Depigmented Centella asiatica Extraction by Pretreated with Supercritical Carbon Dioxide Fluid for Wound Healing Application
Centella asiatica has been included in Thai traditional medicinal plants and recipes, as a well-established historical use as a vegetable and tonic. However, when applied in modern formulations, the
Comparison of the effects of collagenase and extract of Centella asiatica in an experimental model of wound healing: An immunohistochemical and histopathological study
TLDR
Collagenase ointment significantly improves the quality of wound healing and scar formation and is a more appropriate treatment choice than extract of C. asiatica in the early stages of the wound healing process.
Advanced formulation and pharmacological activity of hydrogel of the titrated extract ofC. asiatics
TLDR
Solubility of TECA was dramatically improved by using nonionic and anionic surfactant systems, and Na-DOC was found to be the most effective solubilizer of Teca in formulating a TECA-containing hydrogel typed ointment.
Effect of Centella asiatica L (Umbelliferae) on Normal and Dexamethasone-Suppressed Wound Healing in Wistar Albino Rats
TLDR
The results indicated that the leaf extract of C asiatica promotes wound healing significantly and is able to overcome the wound-healing suppressing action of dexamethasone in a rat model.
Triterpene Composition and Bioactivities of Centella asiatica
TLDR
The potential application of Centella in food and pharmaceutical industries is now widely open as its triterpene composition and bioactivity was compared to grape seed extract and Vitamin C and its lipolytic activity was observed by the release of glycerol.
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