Triterpene saponins from Clematis mandshurica and their antiproliferative activity.

@article{Gong2013TriterpeneSF,
  title={Triterpene saponins from Clematis mandshurica and their antiproliferative activity.},
  author={Yi-Xia Gong and Huiming Hua and Yong-Nan Xu and Jian-Yu Liu and Zong-Gui Yu and Jing Sheng Ma and Hui Zhang and Yong-kui Jing},
  journal={Planta medica},
  year={2013},
  volume={79 11},
  pages={987-94}
}
Six new triterpene saponins, clematomandshurica saponins F-K (1-6), together with a known compound (7), were isolated from the roots and rhizomes of Clematis mandshurica. Their structures were elucidated on the basis of spectroscopic evidence and hydrolysis. Compounds 5-7 exhibited antiproliferative effects against PC-3 human prostate cancer cells with GI50… CONTINUE READING