Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells

@article{Kang2009TriptolideinducedSO,
  title={Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells},
  author={Dong Woo Kang and Ji Young Lee and Deuk-hee Oh and Seon Yang Park and Tae Min Woo and Mi Kyoung Kim and Mi Park and Young Hoon Jang and Do Sik Min},
  journal={Experimental & Molecular Medicine},
  year={2009},
  volume={41},
  pages={678-685}
}
In spite of the importance of phospholipase D (PLD) in cell proliferation and tumorigenesis, little is known about the molecules regulating PLD expression. Thus, identification of small molecules inhibiting PLD expression would be an important advance for PLD-mediated physiology. We examined one such here, denoted "Triptolide", which was identified in a… CONTINUE READING