Triptolide ameliorates lipopolysaccharide-induced acute lung injury in rats

  title={Triptolide ameliorates lipopolysaccharide-induced acute lung injury in rats},
  author={Jianling Gao and Ying Zhan and Jun Chen and Lina Wang and Jianping Yang},
  booktitle={European journal of medical research},
BACKGROUND Acute lung injury (ALI) is a serious clinical syndrome with a high rate of mortality. In this study, the effects of triptolide on lipopolysaccharide (LPS)-induced ALI in rats were investigated. METHODS Sixty-five male Sprague Dawley rats(approved by ethics committee of the First Affiliated Hospital of Soochow University) were randomly divided into five groups. The control group was injected with 2.5 mL saline/kg body weight via the tail vein and intraperitoneally with 1% dimethyl… CONTINUE READING


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