Corpus ID: 75334433

Triptergium wilfordii polyglucoside interfere the expression of TGF-β1、BMP-7 and Gremlin in renal tissue of diabetic nephropathy rats

@article{Weidong2012TriptergiumWP,
  title={Triptergium wilfordii polyglucoside interfere the expression of TGF-$\beta$1、BMP-7 and Gremlin in renal tissue of diabetic nephropathy rats},
  author={Cheng Wei-dong},
  journal={Chinese Journal of Nephrology,Dialysis \& Transplantation},
  year={2012}
}
  • Cheng Wei-dong
  • Published 2012
  • Medicine
  • Chinese Journal of Nephrology,Dialysis & Transplantation
Objective:To observing the effect of tripterygium wilfordii polyglucosides on the expression of transforming growth factor-β1(TGF-β1)、bone morphogenetic protein (BMP-7) and Gremlin in renal tissue of diabetic nephropathy rats,to explain the mechanism of triptergium wilfordii polyglucoside delay renal interstitial fibrosis. Methodology:Forty Sprague-Dawlay (SD) rats were randomly divided into normal control group,diabetes mellitus control group (group DN) and triptergium wilfordii polyglucoside… Expand
1 Citations
The Active Compounds and Therapeutic Target of Tripterygium wilfordii Hook. f. in Attenuating Proteinuria in Diabetic Nephropathy: A Review
  • Peng Liu, Jing Zhang, +4 authors Xinping Qiu
  • Medicine
  • Frontiers in Medicine
  • 2021
TLDR
An overview of the current findings related to the effects and mechanisms of TWHF and its active compounds in therapies of DN is presented, thus providing a systematic understanding of the mechanisms and therapeutic targets by which TWHFs affect cells and tissues in vitro and in vivo. Expand